I've pretty much done everything that can be done with the game at this point, broken down to incremental goals:
Win it (escape) with various builds (melee only, ranged only, no-combat skills), multiple times.
Uncovered the entire map via scouting every land hex on foot.
Killed 100 Dogmen, 100 Blue Frogs, 100 DMC Guards (that was tedious).
Killed the Mergawraith, the Enfield Horror, and many DMC drones.
Survived getting infected with Blue Rot.
I think that when I finish this run, I'll park the game for a while. It's been well worth the purchase price.